Electrochemical Characteristics of Osteoblast Cultured Ti-Ta Alloy for Dental Implant
골아세포가 배양된 치과 임플란트용 Ti-Ta합금의 전기화학적 특성
김원기;최한철;고영무;
Kim, W.G.;Choe, H.C.;Ko, Y.M.;
조선대학교 치과대학 생체재료학교실 및 생체재료나노계면할성화센터, 2단계 BK21;
Department of Dental Materials & Research Center of Nano-Interface Activation for Biomaterials, College of Dentistry, 2nd Stage of Brain Korea 21 for College of Dentistry;
DOI : 10.5695/JKISE.2008.41.2.069
Electrochemical behaviors of surface modified and MC3T3-E1 cell cultured Ti-30Ta alloys have been investigated using various electrochemical methods. The Ti alloys containing Ta were melted by using a vacuum furnace and then homogenized for 6 hrs at $1000^{circ}C$. MC3T3-E1 cell culture was performed with MC3T3-E1 mouse osteoblasts for 2 days. The microstructures and corrosion resistance were measured using FE-SEM, XRD, EIS and potentiodynamic test in artificial saliva solution at $36.5{pm}1^{circ}C$. Ti-Ta alloy showed the martensite structure of ${alpha}+{eta}$ phase and micro-structure was changed from lamellar structure to needle-like structure as Ta content increased. Corrosion resistance increased as Ta content increased. Corrosion resistance of cell cultured Ti-Ta alloy increased predominantly in compared with non cell cultured Ti- Ta alloy due to inhibition of the dissolution of metal ion by covered cell. $R_p$ value of MC3T3-E1 cell cultured Ti-40 Ta alloy showed $1.60{ imes}10^6{Omega}cm^2$ which was higher than those of other Ti alloy. Polarization resistance of cell-cultured Ti-Ta alloy increased in compared with non-cell cultured Ti alloy.
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